Regulators of regulatory pathway: RsmA regulatory pathway

All displayed regulators are experimentally validated.


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0007 experimental Y880_04683 (pnp) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0008 experimental PA0527.1 (RsmY) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NZ_CP020659) 586867..586990 (+) - RsmA (Y880_06257) (↓)
REG0009 experimental PA3621.1 (RsmZ) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NZ_CP020659) 4057543..4057658 (-) - RsmA (Y880_06257) (↓)
REG0010 experimental Y880_06257 (rsmA) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental Y880_05180 (rmsF) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0040 experimental PA0592 (RsmA) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental PA5183a (RsmN) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0157 experimental rmsF T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PA103 chromosome (NZ_JARI00000000) - - tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental PA14_52570 (RsmA) T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0162 experimental RsmY T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 596840..596963 (+) Unknown
REG0163 experimental RsmZ T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1500352..1500467 (+) Unknown
REG0333 experimental rsmA T6SS01269 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa cystic fibrosis isolate CHA chromosome (-) - - hcp1 expression and secretion (↑)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0007 experimental Y880_04683 (pnp) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0010 experimental Y880_06257 (rsmA) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental Y880_05180 (rmsF) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0040 experimental PA0592 (RsmA) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental PA5183a (RsmN) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0157 experimental rmsF T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PA103 chromosome (NZ_JARI00000000) - - tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental PA14_52570 (RsmA) T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0333 experimental rsmA T6SS01269 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa cystic fibrosis isolate CHA chromosome (-) - - hcp1 expression and secretion (↑)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0008 experimental PA0527.1 (RsmY) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NZ_CP020659) 586867..586990 (+) - RsmA (Y880_06257) (↓)
REG0009 experimental PA3621.1 (RsmZ) T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NZ_CP020659) 4057543..4057658 (-) - RsmA (Y880_06257) (↓)
REG0162 experimental RsmY T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 596840..596963 (+) Unknown
REG0163 experimental RsmZ T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1500352..1500467 (+) Unknown